Family Guy Season 12, Episode 6 titled "Life of Brian" is a game changer for the animated FOX show. It had long been rumored that a regular character would be killed off from the show and it finally happened. The premise of tonight's episode: Stewie decides to destroy his time machine after too many close calls with altering the course of mankind when he and Brian travel back to 17th Century Jamestown. After he destroys his time machine, Stewie immediately regrets his decision when an unthinkable event happens, and he is unable to go back in time. RELATED: Best Brian Griffin Quotes: Plus Watch Top 10 Moments From Beloved 'Family Guy' Dog

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Brian died and is now being replaced by a "pooch with attitude" named Vinnie. The new character is voiced by Tony Sirico, best known for starring in "The Sopranos." The pet is replacing Brian who died being run over by a car. Stewie was obviously devastated by what seemed unimaginable and with his time machine broken, the Griffin family could not go back and change the course of events that lead to the death of Brian, a character voiced by creator Seth MacFarlane. He recently talked to The Hollywood Reporter and said that he was waiting for fans to lose interest on the show as he feels it should have ended a long time ago. Seth said, "I talk to the fans and in a way I’m kind of secretly hoping for them to say we’re done with it. There are plenty of people who say the show is kind of over the hill…but the vast majority go pale in the face when I mention the possibility." 

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Brian was an integral part of "Family Guy" and his loss is not only going to be felt within the Griffin family, but will also be felt with fans from the show. Brian, a talking dog, was the most normal character out of all of the quirky characters. Stewie, the talking baby, always had secre thing for him and often mad advances at him. Will his relationship with Vinnie be similar? Will the public accept the new character? Is this the beginning of the end for "Family Guy?" Sound-off with your thoughts below and tell us what your favorite Brian episode was.

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